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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK1
All Species:
26.06
Human Site:
T373
Identified Species:
47.78
UniProt:
Q96SB4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB4
NP_003128.3
655
74325
T373
T
Q
N
S
N
N
E
T
L
R
H
K
E
D
L
Chimpanzee
Pan troglodytes
XP_518428
831
92792
T549
T
Q
N
S
N
N
E
T
L
R
H
K
E
D
L
Rhesus Macaque
Macaca mulatta
XP_001116721
831
92803
T549
T
Q
N
S
N
S
E
T
L
R
H
K
E
D
L
Dog
Lupus familis
XP_850330
823
92006
T541
T
E
N
S
N
K
E
T
L
R
L
K
E
D
L
Cat
Felis silvestris
Mouse
Mus musculus
O70551
648
73070
T373
P
E
N
S
N
N
E
T
L
R
H
K
E
D
L
Rat
Rattus norvegicus
NP_001020897
655
73837
T373
T
A
N
S
N
N
E
T
L
R
L
K
E
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516210
528
59280
I296
S
D
S
C
A
P
L
I
S
D
T
M
V
C
Q
Chicken
Gallus gallus
XP_419265
754
84415
S469
P
D
S
G
S
Q
G
S
V
Q
L
E
D
D
L
Frog
Xenopus laevis
NP_001085122
605
68633
S354
S
S
S
L
D
S
P
S
E
Q
P
S
E
V
P
Zebra Danio
Brachydanio rerio
NP_001074138
640
71523
D356
P
E
D
E
Q
S
L
D
V
Q
Q
Q
M
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
D480
V
R
S
A
D
P
N
D
I
G
C
H
K
V
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
F195
R
K
N
N
Y
R
S
F
P
I
D
L
V
R
E
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
H452
S
F
L
N
S
V
P
H
S
V
T
R
M
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
78.2
76.7
N.A.
91.4
91.4
N.A.
65.5
70.1
67.6
64.7
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
100
78.6
78.5
77.6
N.A.
94.6
94
N.A.
70.3
77.3
78.1
76.1
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
0
13.3
6.6
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
13.3
60
46.6
40
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
0
16
8
0
16
0
0
16
0
8
8
0
8
54
8
% D
% Glu:
0
24
0
8
0
0
47
0
8
0
0
8
54
0
8
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
31
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
8
% I
% Lys:
0
8
0
0
0
8
0
0
0
0
0
47
8
8
0
% K
% Leu:
0
0
8
8
0
0
16
0
47
0
24
8
0
0
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
16
0
0
% M
% Asn:
0
0
54
16
47
31
8
0
0
0
0
0
0
0
0
% N
% Pro:
24
0
0
0
0
16
16
0
8
0
8
0
0
0
8
% P
% Gln:
0
24
0
0
8
8
0
0
0
24
8
8
0
0
8
% Q
% Arg:
8
8
0
0
0
8
0
0
0
47
0
8
0
8
0
% R
% Ser:
24
8
31
47
16
24
8
16
16
0
0
8
0
0
0
% S
% Thr:
39
0
0
0
0
0
0
47
0
0
16
0
0
0
0
% T
% Val:
8
0
0
0
0
8
0
0
16
8
0
0
16
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _